Location: I-64 and I-255, Caseyville Just after the I-255 exit we’re a half mile from Route 157. Location: I-64 and I-255, Caseyville Reassurance shield as US 50 joins I-64. Location: I-64 and Bluff Rd, Caseyville Exit for Illinois 157.  E to IL-159, W to IL-111  W to IL-15, E to IL-159  N to I-55/I-70/US-40, S … Continue reading Interstate 64, I-255/US-50 to IL-157